Dravet Pills

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Dravet C. The core Dravet syndrome phenotype. Epilepsia 52 (suppl 2) 3-9.2011
Speaking about Dravet Childs….
Every child is a person, with his own genetic and acquired characteristics, and must be considered as unique and treated according to his own personality.

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Hattori et al. A screenig test for the prediction of Dravet syndrome before one year of age Epilepsia. 2008 49, 626-33.
The items emcompased in the calculation of a risk score were as follows:
- Onset at or before 7 months = 2 - 5 or more convuslive seizures in the first year = 3 - Hemiconvulsions = 3 - Focal seizures = 1 - Prolonged (more than 10 min) seizures = 3 - Hot water induced seizures = 2 - Presence of an SCN1A missense mutation = 1 - Presence of an SCN1A trucanting mutation = 1
A total clinical score of six or above was the cutoff value indicating a high risk.

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Ceulemans in developmental medicine & child neurology april 2011 vol 53
Thirty years ago, the mortality rate associated with Dravet Syndrome was estimated to be as high as 10 to 15 %, but recent surveys estimate it to be approximately 5 %. This difference is possibly due to adequate prevention, better seizure treatment and a better choice of anti-epileptic drugs.